Best Face Serums Revealed: 5 Picks for Ageless, Hydrated Skin

Woman applying facial serum

Having dry, tight, and flaky skin can be a real hassle. Especially when it feels like you've tried every skincare product under the sun. When it comes to hydrating the skin, most people think of using a moisturizer.

They do a good job of providing basic hydration for most skin types. But if your moisturizer just isn't doing the job, it might be time to consider a face serum. In other words, they're packed with powerful ingredients that get down into your skin to moisturize exactly where it's needed. We've picked out 5 of the best face serums for dry skin to help you choose the perfect one for you. Explore our top face serums for dry skin and unlock the secret to nourished, glowing skin.

Understanding dry skin and its causes

Dry skin can be a real pain, literally. For example, it gets flaky, itchy, and just plain uncomfortable. In the worst cases, it might even crack and bleed, and nobody wants that. Keeping your skin moisturized and bringing back that natural softness is super important, especially as you get older.

So what causes dry skin? Well, there are several reasons this can happen. Cold weather, dry air, and hot showers are some of the usual suspects. Plus, using strong soaps or skincare products can dry out your skin as well. Dry skin can also be the result of certain health conditions and medications.

The importance of hydration for dry skin

Hydration is crucial for dry skin. Well-moisturized skin has a plumper, more youthful appearance. As a result you get a radiating and healthy glow that goes beyond surface-level beauty. But the benefits of hydration aren't just about looks. Hydration plays a pivotal role in enhancing skin elasticity. This elasticity is certainly key to minimizing the appearance of fine lines and wrinkles. With regular hydration, you can see a smoother, more even complexion looking back at you in the mirror.

If you experience dry skin, then adding a serum to your routine can make all the difference. Properly hydrated skin is better equipped to handle environmental stressors and maintain its barrier function. That is to say this protective barrier plays a pivotal role in sealing in moisture and warding off the roughness and flakiness typical of dry skin.

How do face serums work for people with dry skin?

In short, face serums work by delivering a concentrated dose of active ingredients directly into the skin. These ingredients penetrate the skin and help to improve issues like dryness, wrinkles, and rough texture.

Most face serums are also lightweight and fast-absorbing. They are easy to apply, and they make any skincare routine even better. Furthermore, they can be used by themselves or layered underneath your moisturizer for an added boost of hydration.

Key ingredients in the best face serums for dry skin

When it comes to face serums for dry skin, it's all about the ingredients. Look for options that are clinically proven to lock in moisture and strengthen the skin's natural barrier. Here are some ingredients to look for:

Hyaluronic acid: This is a powerful humectant; it attracts moisture to plump and hydrate skin.

Ceramides: These fats boost hydration and strengthen the skin's barrier to lock in moisture.

Vitamin E: A helpful antioxidant, it protects your skin from the sun's harsh UV rays.

Glycerin: This ingredient acts like a magnet to attract water to the skin to hold in hydration.

The best face serums for dry skin

Dr. Diamond's Metacine InstaFacial® Plasma

Elevate your skincare regimen with Dr. Diamond's Metacine InstaFacial® Plasma. Formulated with bioengineered human identical growth factors that simulate platelet-rich plasma’s ability to support skin repair & rejuvenation.


Key Ingredients: Bio-identical Human-Like Growth Factors, Peptides, Sodium Hyaluronate.

Texture: Plasma exudes the feel of a weightless fluid for maximum absorption.

Proven Results: Enhances firmness, tightness, and brightness of the skin.

Usage: Apply one dropperful to face and neck after cleansing, morning and night.

Fortified with Sodium Hyaluronate, this weightless fluid leaves skin looking more lifted, firmer, tighter & luminous. Results increase exponentially with continued use.

InstaFacial® Plasma

Bioactive growth factor serum.

Regular price $200
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Purigenex Intensive Collagen Serum

Purigenex's Collagen Serum is crafted with the purest atelocollagen for unparalleled skin benefits.


Key Ingredients: High-quality atelocollagen and hyaluronic acid.

Quality: FDA-registered, preservative-free. Ideal for sensitive skin.

Proven Results: Boosts skin's collagen, revealing a youthful appearance.

Usage: Keep refrigerated. Apply as directed and return to the fridge afterward.

Note: Delivered in refrigerated packs. Use within one year for best results.

This collagen serum promises delayed cell aging and smoother wrinkles, especially around the neck and eyes. Make sure to refrigerate for optimum efficacy.

Purigenex Intensive Collagen Serum

Regular price $299
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Restorsea PRO Intensive Treatment 10X Serum

This face serum is a gentler alternative to retinols, moreover it outperforms glycolic acid in reducing brown spots.


Key Ingredients: Aquabeautine XL® (Hydrolyzed Roe), Brown Algae, Xylitylglucoside, Squalane.

Benefits: Soothes, hydrates, restores suppleness, and prevents moisture loss.

Proven Results: Effective at reducing the appearance of brown spots.

Usage: Twice daily (morning and evening) on clean skin. Optimal under PRO lotions or creams.

This serum offers a non-irritating solution for brighter and revitalized skin so it's safe for daily use.

Restorsea PRO Intensive Treatment 10X Serum

Regular price $205
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SkinMedica Lumivive System Day and Night

This is a two-step regimen designed to fortify your skin against daily environmental challenges while rejuvenating it overnight.


System Components: LUMIVIVE® Day Damage Defense Serum & LUMIVIVE® Night Revitalize Repair Complex.


  • Overnight Recharge: Enhances skin's natural night repair.
  • Daily Defense: Shields against pollution and blue light throughout the day.
  • Versatile Use: Amplifies any skincare routine.

Proven Results: Achieve radiant skin in as little as 14 days.

Key Ingredients (Day): Niacinamide, Polygonum Aviculare Extract, Ubiquinone, Tremella Fuciformis Sporocarp Extract.

Key Ingredients (Night): Mitoquinol Mesylate, Acetyl Tetrapeptide-2, Vitis Vinifera (Grape) Flower Cell Extract.

This system will reinforce your skin's natural defenses and healing process. In addition, it's tailored for 24/7 protection and recovery.

SkinMedica Lumivive System Day & Night

Regular price $268
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SkinMedica Lytera 2.0

An expertly crafted pigment correcting serum, designed to combat stubborn skin discoloration.


Key Ingredients: Niacinamide, Phenylethyl Resorcinol, Tranexamic Acid, Vitis Vinifera (Grape) Flower Cell Extract.

Benefits: Addresses even the most persistent skin discoloration across all skin types, showing improvements as early as 2 weeks.

Proven Results: An optimal pairing with in-office treatments such as chemical peels, lasers, and microdermabrasion.

Usage: Apply to the affected areas on clean skin. However, you can discuss additional treatment options with a physician.

Lytera® 2.0 is a paraben-free, fragrance-free, and non-comedogenic formulation that offers a radiant and even-toned complexion.

SkinMedica Instant Bright Eye Cream

Regular price $88
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How to incorporate face serums into your skincare routine

Applying a facial serum is an effective way to boost your skincare. Here's a step-by-step way to add it to your daily routine:

  1. Cleanse: Firstly, wash your face with a cleanser to remove any dirt or oil. This prepares your skin to absorb the serum's nutrients.
  2. Tone: Secondly, apply a toner after cleansing to balance the skin and restore its natural pH levels.
  3. Apply the serum: Now for the main event. Take a few drops of serum (you don’t need a lot) on your fingertips or directly on your face. Gently tap or massage it into your skin. Don’t rub too hard—let your skin naturally absorb the serum. Focus on areas that need the most attention, like any dry spots or wrinkles.
  4. Wait a Minute: After that, give it a minute or two to fully absorb. This prevents any pilling that might happen when products are layered too quickly.
  5. Moisturize: Seal in the serum with your favorite moisturizer to lock in the benefits and keep your skin hydrated.
  6. Sunscreen (AM Routine): If it’s morning, you can finish with sunscreen to protect your skin from harmful UV damage.

Remember, serums are super concentrated, so a little goes a long way—once or twice a day should do the trick. And above all, pay attention to your skin. If it starts to feel irritated, scale back so your skin can adapt.

Tips for maximizing the benefits of face serums for dry skin

  • Use a face serum with hyaluronic acid to boost hydration.
  • Layer your serum underneath your moisturizer for extra hydration.
  • Apply your serum to slightly damp skin for better absorption.
  • Don't forget your neck and décolletage; they need hydration too!
  • Use your face serum twice a day for maximum benefits.

Common mistakes to avoid when using face serums for dry skin

  • Using too much serum: A little goes a long way; use only a few drops!
  • Applying the serum to dry skin.
  • Not following with moisturizer.
  • Using a serum with harsh ingredients that can dry out your skin, like alcohol or fragrance.

Achieve a hydrated and glowing complexion with the best face serums for dry skin

Dry skin can be annoying and uncomfortable, but a face serum can help. Choose a serum with moisturizing ingredients like hyaluronic acid, ceramides, and vitamin E. Likewise, be sure to use it as part of your daily skincare routine for the best results. 

To sum up, with the right face serum, you can say goodbye to dryness and hello to a luminous and healthy complexion. So, what are you waiting for? Start exploring our top face serums for dry skin and get ready to glow!